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Camille Lévy

Associate Professor at UCLy

Research group (7) Biotechnologies, health and ethics

clevy@univ-catholyon.fr

Campus Lyon - Saint Paul
10 Place des archives 69002 Lyon

Function

  • Associate Professor, ESTBB Lyon Catholic University
  • Member of the Research group (7) Biotechnologies, health and ethics, UR CONFLUENCE : Sciences et Humanités (EA1598) Lyon Catholic University

Further information

Research areas

Virology Gene therapy Drug discovery

Teaching areas

Molecular biology Cellular Biology Biochemistry

Presentation

Camille Lévy is a Biosciences engineer who graduated from INSA Lyon and holds a PhD in Life Sciences. She is a member of the CONFLUENCE: Sciences and Humanities research unit (EA1598), where she conducts research on risk factors for liver cancer in West Africa and on the mechanisms of hepatic carcinogenesis. Her research also focuses on identifying molecules with therapeutic potential, developing innovative biotherapies and evaluating them in preclinical models. In parallel with her research activities, she is a scientific expert for the UCLy Biotechnology Engineering programme at ESTBB, where she contributes to the deployment of an industrial bioproduction platform and teaches courses.
  • Scientific Publications & Communications
    • Articles In Peer-Reviewed Journals
      • FREITAS, Natalia, ENGUEHARD, Margot, DENOLLY, Solène, LÉVY, Camille, NEVEU, Gregory, LEROLLE, Solène, DEVIGNOT, Stephanie, WEBER, Friedemann, BERGERON, Eric, LEGROS, Vincent, COSSET, François-Loïc (2020). «The interplays between Crimean-Congo hemorrhagic fever virus (CCHFV) M segment-encoded accessory proteins and structural proteins promote virus assembly and infectivity». PLoS Pathogens, 16, 9, e1008850. [+]
      • BERNADIN, Ornellie, AMIRACHE, Fouzia, GIRARD-GAGNEPAIN, Anais, MOIRANGTHEM, Ranjita Devi, LÉVY, Camille, MA, Kuiying, COSTA, Caroline, NÈGRE, Didier, REIMANN, Christian, FENARD, David, CIESLAK, Agata, ASNAFI, Vahid, SADEK, Hanem, MHAIDLY, Rana, CAVAZZANA, Marina, LAGRESLE-PEYROU, Chantal, COSSET, François-Loïc, ANDRÉ, Isabelle, VERHOEYEN, Els (2019). «Baboon envelope LVs efficiently transduced human adult, fetal, and progenitor T cells and corrected SCID-X1 T-cell deficiency». Blood Advances, 3, 3, 461-475. [+]
      • LÉVY, Camille, AMIRACHE, Fouzia, GIRARD-GAGNEPAIN, Anais, FRECHA, Cecilia, ROMAN-RODRÍGUEZ, Francisco J., BERNADIN, Ornellie, COSTA, Caroline, NÈGRE, Didier, GUTIERREZ-GUERRERO, Alejandra, VRANCKX, Lenard S., CLERC, Isabelle, TAYLOR, Naomi, THIELECKE, Lars, CORNILS, Kerstin, BUEREN, Juan A., RIO, Paula, GIJSBERS, Rik, COSSET, François-Loïc, VERHOEYEN, Els (2017). «Measles virus envelope pseudotyped lentiviral vectors transduce quiescent human HSCs at an efficiency without precedent». Blood Advances, 1, 23, 2088-2104. [+]
      • COSTA, C, HYPOLITE, G, BERNADIN, O, LÉVY, Camille, COSSET, F-L, ASNAFI, V, MACINTYRE, E, VERHOEYEN, E, TESIO, M (2017). «Baboon envelope pseudotyped lentiviral vectors: a highly efficient new tool to genetically manipulate T-cell acute lymphoblastic leukaemia-initiating cells». Leukemia, 31, 4, 977-980. [+]
      • VERHOEYEN, Els, ROMAN-RODRIGUEZ, Francisco, COSSET, Francois-Loic, LÉVY, Camille, RIO, Paula (2017). «Gene Therapy in Fanconi Anemia: A Matter of Time, Safety and Gene Transfer Tool Efficiency». Current Gene Therapy, 16, 5, 297-308. [+]
      • LÉVY, Camille, FUSIL, F., AMIRACHE, F., COSTA, C., GIRARD-GAGNEPAIN, A., NEGRE, D., BERNADIN, O., GARAULET, G., RODRIGUEZ, A., NAIR, N., VANDENDRIESSCHE, T., CHUAH, M., COSSET, F-L., VERHOEYEN, E. (2016). «Baboon envelope pseudotyped lentiviral vectors efficiently transduce human B cells and allow active factor IX B cell secretion in vivo in NOD/SCID gamma c -/- mice». Journal of Thrombosis and Haemostasis, 14, 12, 2478-2492. [+]
      • LABENSKI, Verena, SUERTH, Julia D., BARCZAK, Elke, HECKL, Dirk, LÉVY, Camille, BERNADIN, Ornellie, CHARPENTIER, Emmanuelle, WILLIAMS, David A., FEHSE, Boris, VERHOEYEN, Els, SCHAMBACH, Axel (2016). «Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes». Biomaterials, 97, 97-109. [+]
      • LÉVY, Camille, VERHOEYEN, Els, COSSET, François-Loïc (2015). «Surface engineering of lentiviral vectors for gene transfer into gene therapy target cells». Current Opinion in Pharmacology, 24, 79-85. [+]
      • ZHOU, Qi, UHLIG, Katharina M., MUTH, Anke, KIMPEL, Janine, LÉVY, Camille, MÜNCH, Robert C., SEIFRIED, Janna, PFEIFFER, Anett, TRKOLA, Alexandra, COULIBALY, Cheick, VON LAER, Dorothee, WELS, Winfried S., HARTWIG, Udo F., VERHOEYEN, Els, BUCHHOLZ, Christian J. (2015). «Exclusive Transduction of Human CD4 + T Cells upon Systemic Delivery of CD4 - Targeted Lentiviral Vectors». The Journal of Immunology, 195, 5, 2493-2501. [+]
      • GIRARD-GAGNEPAIN, Anais, AMIRACHE, Fouzia, COSTA, Caroline, LÉVY, Camille, FRECHA, Cecilia, FUSIL, Floriane, NÈGRE, Didier, LAVILLETTE, Dimitri, COSSET, François-Loïc, VERHOEYEN, Els (2014). «Baboon envelope pseudotyped LVs outperform VSV-G-LVs for gene transfer into early-cytokine-stimulated and resting HSCs». Blood, 124, 8, 1221-1231. [+]
      • KWEDER, Hasan, AINOUZE, Michelle, COSBY, Sara Louise, MULLER, Claude P., LÉVY, Camille, VERHOEYEN, Els, COSSET, François-Loïc, MANET, Evelyne, BUCKLAND, Robin (2014). «Mutations in the H, F, or M Proteins Can Facilitate Resistance of Measles Virus to Neutralizing Human Anti-MV Sera». Advances in Virology, 2014, 1-18. [+]
      • AMIRACHE, Fouzia, LÉVY, Camille, COSTA, Caroline, MANGEOT, Philippe-Emmanuel, TORBETT, Bruce E., WANG, Cathy X., NÈGRE, Didier, COSSET, François-Loïc, VERHOEYEN, Els (2014). «Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor». Blood, 123, 9, 1422-1424. [+]
      • LÉVY, Camille, AERTS, Laetitia, HAMELIN, Marie-Ève, GRANIER, Christelle, SZÉCSI, Judit, LAVILLETTE, Dimitri, BOIVIN, Guy, COSSET, François-Loïc (2013). «Virus-like particle vaccine induces cross-protection against human metapneumovirus infections in mice». Clinical and vaccine immunology : CVI, 31, 25, 2778-2785.
      • LÉVY, Camille, AMIRACHE, Fouzia, COSTA, Caroline, FRECHA, Cecilia, MULLER, Claude P, KWEDER, Hasan, BUCKLAND, Robin, COSSET, François-Loïc, VERHOEYEN, Els (2012). «Lentiviral Vectors Displaying Modified Measles Virus gp Overcome Pre-existing Immunity in In Vivo-like Transduction of Human T and B Cells». Molecular Therapy, 20, 9, 1699-1712. [+]
      • FRECHA, Cecilia, LÉVY, Camille, COSTA, Caroline, NÈGRE, Didier, AMIRACHE, Fouzia, BUCKLAND, Robin, RUSSELL, Steven J., COSSET, François-Loïc, VERHOEYEN, Els (2011). «Measles Virus Glycoprotein-Pseudotyped Lentiviral Vector-Mediated Gene Transfer into Quiescent Lymphocytes Requires Binding to both SLAM and CD46 Entry Receptors». Journal of virology, 85, 12, 5975-5985. [+]
      • FRECHA, Cecilia, LÉVY, Camille, COSSET, François-Loïc, VERHOEYEN, Els (2010). «Advances in the Field of Lentivector-based Transduction of T and B Lymphocytes for Gene Therapy». Molecular Therapy, 18, 10, 1748-1757. [+]
      • LÉVY, Camille, FRECHA, Cecilia, COSTA, Caroline, RACHINEL, Nicolas, SALLES, Gilles, COSSET, François-Loïc, VERHOEYEN, Els (2010). «Lentiviral vectors and transduction of human cancer B cells». Blood, 116, 3, 498-500. [+]
      • FRECHA, Cecilia, COSTA, Caroline, LÉVY, Camille, NÈGRE, Didier, RUSSELL, Stephen J., MAISNER, Andrea, SALLES, Gilles, PENG, Kah-Whye, COSSET, Francois-Loïc, VERHOEYEN, Els (2009). «Efficient and stable transduction of resting B lymphocytes and primary chronic lymphocyte leukemia cells using measles virus gp displaying lentiviral vectors». Blood, 114, 15, 3173-3180. [+]
    • Presentations at Symposiums
      • Conference paper
        • LÉVY, Camille. «Engineered pseudotyped lentiviral vectors to allow gene transfer into hematopoietic cells». Life Science Meeting, IMC Krems - University of Applied Sciences, May 2024, Krems, Austria. [By invitation].
        • LÉVY, Camille, AMIRACHE, Fouzia, GIRARD-GAGNEPAIN, Anais, FRECHA, Cecilia, COSTA, Caroline, NÈGRE, Didier, COSSET, Francois-Loic, VERHOEYEN, Els. «Measles virus glycoprotein pseudotyped lentiviral vectors transduce resting long-term repopulation hCD34+-cells at an efficiency without precedent.». ESCGT Congress, ESCGT, October 2014, La Haye, Netherlands.
        • LÉVY, Camille, AMIRACHE, Fouzia, COSTA, Caroline, FRECHA, Cecilia, MULLER, Claude P, KWEDER, Hasan, BUCKLAND, Robin, COSSET, Francois-Loic, VERHOEYEN, Els. «A new lentiviral vector tool to evaluate measles virus escape from infection- or vaccine-induced antibodies.». 5 th European Congress of Virology, European Congress of Virology, September 2013, Lyon, France.
  • Scientific valorisation and dissemination of knowledge
    • Products with a Didactic and/or Practical Purpose
      • Chapters
        • LÉVY, Camille, BUCKLAND, Robin, COSSET, F-L, VERHOEYEN, Els (2013). «A new lentiviral vector tool to evaluate measles virus escape from infection- or vaccine-induced antibodies». In : iConcept Press (dir.), Vaccines – Benefits and Risks. CreateSpace, Amazon, Chap 7.
  • Scientific Collaborations
    • Member of research laboratories
      • Since 2022, Member of the Research group (7) Biotechnologies, health and ethics, UR CONFLUENCE : Sciences et Humanités (EA1598), UCLy, France
    • Involvement in subsidised research contracts
      • Member : Déterminants virologiques, environnementaux et socio-structurels du portage chronique du VHB/VHD et du risque de carcinome hépatocellulaire au Sénégal (régions de Kaolack et Kaffrine), ANRS, in partnership with USSEIN – Université du Sine-Saloum El Hadj Ibrahima Niass ; Hôpitaux et centres cliniques de Kaolack ; IHU-institut hospitalo-universitaire de Lyon
    • Involvement in collective research projects
      • Since 2025, Hybrid Intelligence for Innovative Drugs against Emergent Viruses
      • Since 2025, Linking Organism-based Knowledge with Intelligent algorithms
      • Since 2024, Etude multidisciplinaire de l’infection chronique au virus de l’hépatite B et ses cofacteurs de risques de maladie hépatiques dans le Saloum (régions de Kaolack et de Kaffrin, Sénégal
  • Supervision of master's thesis
    • 2024 - 2025, Impact du génotype et de mutations ciblées sur le stress du réticulum endoplasmique induit par les glycoprotéines du VHB, Master's thesis, Université Claude Bernard Lyon 1.
  • Research Evaluation Activities
    • Reviewer of Scientific Publications
      • Since 2014, Reviewer pour des
  • Scientific valorisation and dissemination of knowledge
    • Organisation of scientific mediation events
      • 2025 : Coordination du LabEscape pour la Fête de la Science
      • Since 2021, Animation d'ateliers pour la Fête de la Science
  • Diplomas
    • 2012, Doctorat (PhD), Biologie, Virologie, Nouveaux pseudotypes rétroviraux basés sur les glycoprotéines des paramyxovirus : applications biothérapeutiques en thérapie génique et en vaccinologie, Ecole normale supérieure de Lyon (ENS Lyon), France
    • 2008, Master, Sciences du vivant, Biologie moléculaire et structurale, biochimie, Université Claude Bernard Lyon 1, France
    • 2007, Diplôme d’ingénieur, Biosciences, Biochimie et Biotechnologies, INSA Lyon, France
  • Research professional experiences
    • 2012 - 2018, Postdoctoral researcher, Centre International de Recherche en Infectiologie (CIRI) - UMR 5308, France
  • Pedagogical activities and responsabilities
    • Since 2022, Associate Professor, ESTBB, UCLy, France
    • 2021 - 2022 Head of studies, ESTBB, Lyon Catholic University, France
    • 2020 - 2021 Teacher, Ministère de l'Education Nationale, de la jeunesse et des sports, France
  • Certificates and training
    • 2016 DIU Expérimentation Animale Niveau B (ex Niveau 1), Université Claude Bernard Lyon 1, France
  • Languages
    • French - Able to teach
    • English - Able to teach